Does anyone else suffer from severe cycles of depression related to
the TKI's? I have taken all 3 (Gleevec, Sprycel and Tasigna).

During "vacations" from these drugs and prior to diagnosis, I had
never experienced such severe depressive episodes.

I'm talking about a tornado touchdown with complete devastation to the
point of suicidal ideation. Can't stop crying, hide from the world and
just die. Bleh!

They plop me on various antidepressants every time I start a new TKI,
which are totally ineffective and increases various side effects. I am
one of the oddballs that gets rare side effects and I react badly to
just about everything they give me.

So, I'm probably the oddball who reacts psychologically to these
drugs, too. I can't explain it, control it or avoid it.

Just curious - anyone else?
Kelly

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