Kelly - I've been working with a patient in Texas who has had similar
experiences. I'm glad you wrote about this. He is having trouble getting
help too. Pat

-----Original Message-----
From: cmlhope@goog... [mailto:cmlhope@goog...] On Behalf
Of kellyelise
Sent: Wednesday, April 11, 2012 3:50 PM
To: CMLHope
Subject: [CMLHope] Depressive side effects

Does anyone else suffer from severe cycles of depression related to the
TKI's? I have taken all 3 (Gleevec, Sprycel and Tasigna).

During "vacations" from these drugs and prior to diagnosis, I had never
experienced such severe depressive episodes.

I'm talking about a tornado touchdown with complete devastation to the point
of suicidal ideation. Can't stop crying, hide from the world and just die.
Bleh!

They plop me on various antidepressants every time I start a new TKI, which
are totally ineffective and increases various side effects. I am one of the
oddballs that gets rare side effects and I react badly to just about
everything they give me.

So, I'm probably the oddball who reacts psychologically to these drugs, too.
I can't explain it, control it or avoid it.

Just curious - anyone else?
Kelly

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